Effects of niosomal cisplatin and combination of the same with theophylline and with activated macrophages in murine B16F10 melanoma model

The use of cisplatin is limited due to its certain toxic effects. In the present study niosomes of cisplatin by using span 60 and cholesterol were prepared and investigated for antimetastatic activity in experimental metastatic model of B16F10 melanoma. Theophylline and its combination effect with f...

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Veröffentlicht in:	Cancer biotherapy & radiopharmaceuticals 2002-04, Vol.17 (2), p.183-192
Hauptverfasser:	GUDE, R. P, JADHAV, M. G, RAO, S. G. A, JAGTAP, A. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Antineoplastic Agents - therapeutic use Biological and medical sciences Body Weight Cisplatin - administration & dosage Combined Modality Therapy Combined treatments (chemotherapy of immunotherapy associated with an other treatment) Female Leukocyte Count Liposomes Macrophage Activation Macrophages, Peritoneal - physiology Male Medical sciences Melanoma, Experimental - pathology Melanoma, Experimental - secondary Melanoma, Experimental - therapy Mice Mice, Inbred C57BL Neoplasm Transplantation Pharmacology. Drug treatments Theophylline - administration & dosage Tumor Cells, Cultured
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