Screening of new bioactive in lebui beans (Cajanus sp.) of Lombok

Lebui beans (Cajanus sp.) has been used by Sasak people of Lombok Island West Nusa Tenggara Indonesia as a traditional medicine. The potential compounds found in the lebui bean are thought beneficial mainly for curing the infectious diseases. The aim of this study is to extract and find out the type...

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Veröffentlicht in:International food research journal 2018, Vol.25 (1), p.25-33
Hauptverfasser: Mushollaeni, W, Kumalaningsih, S, Wignyanto, Santoso, I
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creator Mushollaeni, W
Kumalaningsih, S
Wignyanto
Santoso, I
description Lebui beans (Cajanus sp.) has been used by Sasak people of Lombok Island West Nusa Tenggara Indonesia as a traditional medicine. The potential compounds found in the lebui bean are thought beneficial mainly for curing the infectious diseases. The aim of this study is to extract and find out the type of bioactive compound from lebui bean by phytochemicals and screening test. Two stages of the study had been carried out. The first stage was to extract the bioactive compound from lebui bean by solvent extraction and the second stage was to screen the type of bioactive compound by phytochemicals test, Thin Layer Chromatography (TLC) and Gas Chromatography-Mass Spectrometry (GC-MS). The result of the first stage showed that ethanol 70% was best solvent to extract the bioactive compound in lebui bean, and the second stage showed that lebui bean contained alkaloids, flavonoids, polyphenols, terpenoids/steroids, and also 44 constituents of secondary metabolites ie. Neophytadiene, Methyl Laurate, Nonanedioic Acid-Dimethyl Ester, Methyl Myristate, Methyl Pentadecanoate, Methyl Palmitoleate, Methyl Linoleate, Heptadecanoic Acid, 8-Octadecenoic Acid, Methyl Stearate, Eicosanoic Acid, Methyl Tricosanoate, Methyl Lignocerate, 4-Methylimidazole-5-[1,1-Dimethylbutyric Acid Amide], 5,8,1,14-Eicosatetraenoic Acid Methyl Ester, Isopropyl Linoleate, and 8,"-Octadecadienoic Acid.
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subjects Agriculture
Antioxidants
Beans
Biology
Cajanus
Chemistry
Chromatography
Flavonoids
Food
Infectious diseases
Metabolites
Phytochemicals
Polyphenols
Solvent extraction processes
Toxicology
title Screening of new bioactive in lebui beans (Cajanus sp.) of Lombok
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