MOLECULAR MECHANISMS OF GLUCOCORTICOIDS IN THE CONTROL OF INFLAMMATION AND LYMPHOCYTE APOPTOSIS

Abstract The immune system must be tightly controlled not only to guarantee efficient protection from invading pathogens and oncogenic cells but also to avoid exaggerated immune responses and autoimmunity. This is achieved through interactions amongst leukocytes themselves, by signals from stromal c...

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Veröffentlicht in:	Critical reviews in clinical laboratory sciences 2005, Vol.42 (1), p.71-104
Hauptverfasser:	Tuckermann, Jan P., Kleiman, Anna, McPherson, Kirsty G., Reichardt, Holger M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - metabolism Anti-Inflammatory Agents - therapeutic use apoptosis Apoptosis - drug effects Apoptosis - genetics dendritic cells glucocorticoids Glucocorticoids - metabolism Glucocorticoids - therapeutic use Humans immunosuppressants inflammation Inflammation - drug therapy Inflammation - genetics Inflammation - metabolism Lymphocytes - drug effects Lymphocytes - metabolism Lymphocytes - pathology Receptors, Glucocorticoid - drug effects Receptors, Glucocorticoid - genetics Receptors, Glucocorticoid - metabolism thymocytes transcription
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