Decrease of creatinine clearance rate with aging in patients with head and neck cancer in Japan

We aimed to clarify the reason for the lower dosage of cis-platinum (CDDP) in patients with head and neck cancer in Japan compared with that in other countries, by evaluating renal function. We studied 375 patients with head and neck cancer who had been hospitalized from January 1998 to October 2005...

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Veröffentlicht in:	International journal of clinical oncology 2007-04, Vol.12 (2), p.120-124
Hauptverfasser:	Nishimura, Goshi, Tsukuda, Mamoru, Horiuchi, Choichi, Satake, Kenichi, Yoshida, Takafumi, Taguchi, Takahide, Nagao, Junichi, Kawakami, Mariko, Kondo, Norio, Matsuda, Hideki, Mikami, Yasukazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Factors Aged Aged, 80 and over Aging Aging - urine Antineoplastic Agents - administration & dosage Antineoplastic Agents - adverse effects Biomarkers, Tumor - urine Carcinoma, Squamous Cell - drug therapy Carcinoma, Squamous Cell - physiopathology Carcinoma, Squamous Cell - urine Chemotherapy Cisplatin - administration & dosage Cisplatin - adverse effects Creatinine - urine Female Glomerular Filtration Rate - drug effects Head & neck cancer Head and Neck Neoplasms - drug therapy Head and Neck Neoplasms - physiopathology Head and Neck Neoplasms - urine Humans Japan Kidney Failure, Chronic - chemically induced Kidney Failure, Chronic - physiopathology Kidney Failure, Chronic - urine Kidney Function Tests Kidneys Male Middle Aged Oncology Pharmacology
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