V 2+T Cell expansion in crohn's disease: impact of inflammation, disease activity and treatment

Introduction Crohn's disease (CD) is driven by inappropriate inflammatory responses to gut microbiota. Circulating, microbe-responsive Vγ9Vδ2+(δ2)T cells express 'gut-homing' integrin β7 and may contribute to intestinal inflammation. Hypothesis Increased intestinal permeability and mi...

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Veröffentlicht in:	Gut 2011-04, Vol.60 (Suppl 1), p.A148-A148
Hauptverfasser:	Hedin, C. R., McCarthy, N. E., Bhattacharjee, S., James, G., Whelan, K., Lindsay, J. O., Stagg, A. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Azathioprine Cell activation Cell culture Cell proliferation Crohn's disease Digestive system Flow cytometry Gastrointestinal tract Immunosuppressive agents Inflammation Inflammatory bowel diseases Intestinal microflora Intestine Leukocytes (mononuclear) Lymphocytes T Microbiota Patients Peripheral blood mononuclear cells Permeability Siblings Tumor necrosis factor-α γ-Interferon
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