Mutational burden of resectable pancreatic cancer, as determined by whole transcriptome and whole exome sequencing, predicts a poor prognosis

Despite the genomic characterization of pancreatic cancer (PC), marked advances in the development of prognosis classification and novel therapeutic strategies have yet to come. The present study aimed to better understand the genomic alterations associated with the invasive phenotype of PC, in orde...

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Veröffentlicht in:	International journal of oncology 2018-06, Vol.52 (6), p.1972-1980
Hauptverfasser:	Grassi, Elisa, Durante, Sandra, Astolfi, Annalisa, Tarantino, Giuseppe, Indio, Valentina, Freier, Eva, Vecchiarelli, Silvia, Ricci, Claudio, Casadei, Riccardo, Formica, Francesca, Filippini, Daria, Comito, Francesca, Serra, Carla, Santini, Donatella, D' Errico, Antonietta, Minni, Francesco, Biasco, Guido, Di Marco, Mariacristina
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Cell cycle Committees Deoxyribonucleic acid Development and progression DNA DNA damage Gene expression Gene mutation Genes Genetic aspects Genomes Health aspects Medical prognosis Mortality Mutation Pancreatic cancer Patients Proteins Surgery
Online-Zugang:	Volltext
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