A study to examine the relationship between uterine pathology and depletion of oxytetracycline in plasma and milk after intrauterine infusion

An abstract of a study by Gorden et al examining the relationship between uterine pathology and depletion of oxytetracycline (OTC) in plasma and milk after intrauterine infusion in cows is presented. Thirty-two cows received a single treatment of 4 g of OTC via intrauterine infusion. Blood and milk samples were collected before intrauterine therapy and throughout the trial period of 96 h after infusion. Results showed that the use of uterine severity score can be used to predict OTC concentration in the first day following therapy but should not be used as a predictor of OTC concentrations 96 h after treatment.