0932 Sleep Correlates of Nightmares Among Veterans

Abstract Introduction There is an increased prevalence of Nightmare Disorder (ND) among veterans with obstructive sleep apnea (OSA). A further investigation of measured sleep parameters among patients with and without ND correlate with potential co-morbidities. Methods Data presented herein are interim results from an IRB approved study to determine correlates and sequelae of nightmares. Two cohorts of veterans from James A Haley Veterans Hospital between 2007 and 2011 was defined, ND and control. Demographic and sleep study data between January 2006 and April 2016 were pulled from the electronic medical record (EMR) for each cohort. Sleep study data was collected for 92 ND and 73 control veterans. Logistic regression (SAS 9.4) was used to compare arms: Epworth sleepiness scale, Sp02 nadir, apnea-hypopnea index from polysomnography (PSG) or respiratory event index from home sleep test (HST), periodic limb movement (PLM) index, total sleep time (minutes) and sleep staging (PSG). Results Mean age for each group was 55. Sample size was predominately male for ND (91.3%) and control group (93.1%). Regarding demographics (BMI, ethnicity, marital status) there were no significant differences between each group. There was similar distribution among type of study (PSG vs HST) within each group, 63% PSG and 34% HST in ND group vs 67% PSG and 33% HST in control group. After adjusting for demographics, study type, and Charlson co-morbidity index, there was a significantly higher Sp02 nadir (84.0 ± 8.9 vs. 79.7 ± 8.6) and PLM index (26.9 ± 36.4 vs 15.3 ± 26.6) in the ND group vs control group. Conclusion Among veterans in this cohort with sleep study data, those with ND had a significantly less hypoxemia and more PLMs. Our results contradict hypotheses that ND is associated with oxygen deprivation and supports research focusing on differences in arousals, sleep staging, and PLM index. Support (If Any) This material is the result of work supported with resources and the use of facilities at the James A. Haley Veterans’ Hospital.