Ag nanoparticles decorated Fe3O4/chitosan nanocomposite: synthesis, characterization and application toward electrochemical sensing of hydrogen peroxide

We studied a rapid, sensitive and selective amperometric sensor for determination of hydrogen peroxide by electrodeposited Ag NPs on a modified glassy carbon electrode (GCE). The modified GCE was constructed through a step by step modification of magnetic chitosan functional composite (Fe 3 O 4 –CH) and high-dispersed silver nanoparticles on the surface. The resulted Ag@Fe 3 O 4 –CH was characterized by various analytical methods including Fourier transform infrared spectroscopy, X-ray diffraction, transmission electron microscopy, scanning electron microscopy and cyclic voltammetry. The proposed sensor employed Ag@Fe 3 O 4 –CH/GCE as the working electrode with a linear current response to the hydrogen peroxide concentration in a wide range from 0.01 to 400 µM with a low limit of detection (LOD = 0.0038 µM, S / N = 3). The proposed sensor showed superior reproductivity, sensitivity and selectivity for the detection of hydrogen peroxide in environmental and clinical samples.