Baicalin and chrysin mixture imparts cyto-protection against methylglyoxal induced cytotoxicity and diabetic tubular injury by modulating RAGE, oxidative stress and inflammation

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Veröffentlicht in:	Environmental toxicology and pharmacology 2017-03, Vol.50, p.67-75
Hauptverfasser:	Singh, Jyotsna, Chaudhari, Bhushan P, Kakkar, Poonam
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced glycation end products Animals Antioxidants Apoptosis Apoptosis - drug effects Baicalin Biocompatibility Cell Line Chrysin Cytometry Cytotoxicity Depolarization Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - chemically induced Diabetes Mellitus, Experimental - complications Diabetes Mellitus, Experimental - drug therapy Diabetic Nephropathies - drug therapy Diabetic Nephropathies - metabolism Diabetic nephropathy Drug Therapy, Combination Emergency Epithelial cells Epithelial Cells - drug effects Flavonoids Flavonoids - administration & dosage Flavonoids - pharmacology Flow cytometry Glycation End Products, Advanced - analysis In vivo methods and tests Inflammation Kidney diseases Kidneys Male Methylglyoxal Microscopic analysis Mitochondria Mitochondria - drug effects Nephropathy Nitric-oxide synthase Oroxylum indicum Oxidative stress Oxidative Stress - drug effects Protein kinase C Proteins Pyruvaldehyde Pyruvaldehyde - toxicity Rats Reactive Oxygen Species - metabolism Streptozocin Toxicity
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