Surface Imprinting on Spherical Macroporous Silica for Protein Recognition
A novel surface imprinting method on macroporous SiO2 microspheres with highly ordered three-dimensional interconnected structure has been developed for bovine hemoglobin (BHb) protein recognition. The selective experiment showed that the synthesized macroporous microspheres exhibited good specific...
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Veröffentlicht in: | Chemistry letters 2018-05, Vol.47 (5), p.686-689 |
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creator | Xu, DanDan Li, SiQi Pan, Ting He, JianFeng Wu, QuanZhou |
description | A novel surface imprinting method on macroporous SiO2 microspheres with highly ordered three-dimensional interconnected structure has been developed for bovine hemoglobin (BHb) protein recognition. The selective experiment showed that the synthesized macroporous microspheres exhibited good specific recognition for template molecules. Compared with the traditional bulk imprinted polymers, the surface imprinting microspheres showed higher binding kinetic behavior, and its binding rate constant was nearly about 7 times as large as that of the bulk imprinted polymers. |
doi_str_mv | 10.1246/cl.180050 |
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The selective experiment showed that the synthesized macroporous microspheres exhibited good specific recognition for template molecules. Compared with the traditional bulk imprinted polymers, the surface imprinting microspheres showed higher binding kinetic behavior, and its binding rate constant was nearly about 7 times as large as that of the bulk imprinted polymers.</description><identifier>ISSN: 0366-7022</identifier><identifier>EISSN: 1348-0715</identifier><identifier>DOI: 10.1246/cl.180050</identifier><language>eng</language><publisher>Tokyo: The Chemical Society of Japan</publisher><subject>Binding ; Chemical synthesis ; Hemoglobin ; Imprinted polymers ; Microspheres ; Molecular chains ; Recognition ; Silicon dioxide</subject><ispartof>Chemistry letters, 2018-05, Vol.47 (5), p.686-689</ispartof><rights>The Chemical Society of Japan</rights><rights>Copyright Chemical Society of Japan 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-389045f486c2d685e7fd3148ff17ac189b9550a49ffc6d5a412f944e712944203</citedby><cites>FETCH-LOGICAL-c414t-389045f486c2d685e7fd3148ff17ac189b9550a49ffc6d5a412f944e712944203</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Xu, DanDan</creatorcontrib><creatorcontrib>Li, SiQi</creatorcontrib><creatorcontrib>Pan, Ting</creatorcontrib><creatorcontrib>He, JianFeng</creatorcontrib><creatorcontrib>Wu, QuanZhou</creatorcontrib><title>Surface Imprinting on Spherical Macroporous Silica for Protein Recognition</title><title>Chemistry letters</title><description>A novel surface imprinting method on macroporous SiO2 microspheres with highly ordered three-dimensional interconnected structure has been developed for bovine hemoglobin (BHb) protein recognition. The selective experiment showed that the synthesized macroporous microspheres exhibited good specific recognition for template molecules. Compared with the traditional bulk imprinted polymers, the surface imprinting microspheres showed higher binding kinetic behavior, and its binding rate constant was nearly about 7 times as large as that of the bulk imprinted polymers.</description><subject>Binding</subject><subject>Chemical synthesis</subject><subject>Hemoglobin</subject><subject>Imprinted polymers</subject><subject>Microspheres</subject><subject>Molecular chains</subject><subject>Recognition</subject><subject>Silicon dioxide</subject><issn>0366-7022</issn><issn>1348-0715</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNplkE1LAzEQhoMoWKsH_0HAk4et-dxNjlL8qFQUq-cQ06RN2SZrsnvovzelBQ-eXph55p15B4BrjCaYsPrOtBMsEOLoBIwwZaJCDeanYIRoXVcNIuQcXOS8QQgJSckIvCyG5LSxcLbtkg-9DysYA1x0a5u80S181SbFLqY4ZLjwbalBFxN8T7G3PsAPa-Iq-N7HcAnOnG6zvTrqGHw9PnxOn6v529Nsej-vDMOsr6iQiHHHRG3IshbcNm5JMRPO4UYbLOS35BxpJp0z9ZJrhomTjNkGkyIE0TG4Ofh2Kf4MNvdqE4cUykpVukxiSjkp1O2BKufnnKxTJd9Wp53CSO1fpUyrDq8qbH1k13a7T52j8bbfbXSnw5_7_8Ff1_1tNg</recordid><startdate>20180505</startdate><enddate>20180505</enddate><creator>Xu, DanDan</creator><creator>Li, SiQi</creator><creator>Pan, Ting</creator><creator>He, JianFeng</creator><creator>Wu, QuanZhou</creator><general>The Chemical Society of Japan</general><general>Chemical Society of Japan</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope></search><sort><creationdate>20180505</creationdate><title>Surface Imprinting on Spherical Macroporous Silica for Protein Recognition</title><author>Xu, DanDan ; Li, SiQi ; Pan, Ting ; He, JianFeng ; Wu, QuanZhou</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-389045f486c2d685e7fd3148ff17ac189b9550a49ffc6d5a412f944e712944203</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Binding</topic><topic>Chemical synthesis</topic><topic>Hemoglobin</topic><topic>Imprinted polymers</topic><topic>Microspheres</topic><topic>Molecular chains</topic><topic>Recognition</topic><topic>Silicon dioxide</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xu, DanDan</creatorcontrib><creatorcontrib>Li, SiQi</creatorcontrib><creatorcontrib>Pan, Ting</creatorcontrib><creatorcontrib>He, JianFeng</creatorcontrib><creatorcontrib>Wu, QuanZhou</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><jtitle>Chemistry letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xu, DanDan</au><au>Li, SiQi</au><au>Pan, Ting</au><au>He, JianFeng</au><au>Wu, QuanZhou</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surface Imprinting on Spherical Macroporous Silica for Protein Recognition</atitle><jtitle>Chemistry letters</jtitle><date>2018-05-05</date><risdate>2018</risdate><volume>47</volume><issue>5</issue><spage>686</spage><epage>689</epage><pages>686-689</pages><issn>0366-7022</issn><eissn>1348-0715</eissn><abstract>A novel surface imprinting method on macroporous SiO2 microspheres with highly ordered three-dimensional interconnected structure has been developed for bovine hemoglobin (BHb) protein recognition. The selective experiment showed that the synthesized macroporous microspheres exhibited good specific recognition for template molecules. Compared with the traditional bulk imprinted polymers, the surface imprinting microspheres showed higher binding kinetic behavior, and its binding rate constant was nearly about 7 times as large as that of the bulk imprinted polymers.</abstract><cop>Tokyo</cop><pub>The Chemical Society of Japan</pub><doi>10.1246/cl.180050</doi><tpages>4</tpages></addata></record> |
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ispartof | Chemistry letters, 2018-05, Vol.47 (5), p.686-689 |
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language | eng |
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source | Oxford University Press Journals All Titles (1996-Current) |
subjects | Binding Chemical synthesis Hemoglobin Imprinted polymers Microspheres Molecular chains Recognition Silicon dioxide |
title | Surface Imprinting on Spherical Macroporous Silica for Protein Recognition |
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