Multimodal assessment of orbital immune cell infiltration and tissue remodeling during development of graves disease by 1H19F MRI

Purpose To evaluate key molecular and cellular features of Graves orbitopathy (GO) by simultaneous monitoring of alterations in morphology, inflammatory patterns, and tissue remodeling. Methods To this end, we utilized a murine model of GO induced by immunization with a human thyroid‐stimulating hor...

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Veröffentlicht in:	Magnetic resonance in medicine 2018-08, Vol.80 (2), p.711-718
Hauptverfasser:	Flögel, Ulrich, Schlüter, Anke, Jacoby, Christoph, Temme, Sebastian, Banga, J. Paul, Eckstein, Anja, Schrader, Jürgen, Berchner‐Pfannschmidt, Utta
Format:	Artikel
Sprache:	eng
Schlagworte:	19F MRI Animal models Edema Fluorine Glands Graves disease Histology Hyaluronic acid Immune system Immunization Infiltration Inflammation Intravenous administration Magnetic resonance imaging Mapping Mice Myopathy perfluorocarbons Relaxation time remodeling Thyroid Visualization
Online-Zugang:	Volltext
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