Fibrogenic Polymorphisms (TGF-β, PAI-1, AT) in Mexican Patients With Established Liver Fibrosis. Potential Correlation With Pirfenidone Treatment

Background/AimThe aim of this work was to establish a potential correlation between specific polymorphisms and presence of hepatic fibrosis in Mexican patients with established liver fibrosis (ELF). Second, necroinflammatory index improvement was correlated with Pirfenidone (PFD) treatment response...

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Veröffentlicht in:	Journal of investigative medicine 2008-10, Vol.56 (7), p.944-953
Hauptverfasser:	Armendáriz-Borunda, Juan, Rincón, Ana Rosa, Muñoz-Valle, José Francisco, Bueno-Topete, Miriam, Oregón-Romero, Edith, Islas-Carbajal, María Cristina, Medina-Preciado, David, González-García, Ignacio, Bautista, C. Alfredo, García-Rocha, Sergio, Godoy, Jesús, Vázquez-Del Mercado, Mónica, Troyo-SanRoman, Rogelio, Arellano-Olivera, Inmaculada, Lucano, Silvia, Álvarez-Rodríguez, Adriana, Salazar, Adriana
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alcohol Alcohol abuse Alcohol use Angiotensinogen - genetics Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Base Sequence Blood pressure Collagen DNA Primers - genetics Female Genes Growth factors Hepatitis Hepatitis C - drug therapy Hepatitis C - genetics Humans Infections Liver Cirrhosis - drug therapy Liver Cirrhosis - genetics Liver Cirrhosis, Alcoholic - drug therapy Liver Cirrhosis, Alcoholic - genetics Liver diseases Male Metabolism Mexico Middle Aged Plasminogen Activator Inhibitor 1 - genetics Polymorphism, Genetic Pyridones - therapeutic use Transforming Growth Factor beta - genetics
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