Triflic acid-catalyzed metal-free synthesis of ( E )-2-cyanoacrylamides and 3-substituted azetidine-2,4-diones

A TfOH-catalyzed highly efficient synthesis of biologically active ( E )-2-cyanoacrylamides and 3-substituted azetidine-2,4-diones has been reported with 64–94% yields under metal-free conditions. The reaction proceeds through sequential Knoevenagel condensation/stereoselective in situ monohydration...

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Veröffentlicht in:	New journal of chemistry 2018, Vol.42 (8), p.6433-6440
Hauptverfasser:	Rupanwar, Bapurao D., Chavan, Santosh S., Shelke, Anil M., Suryavanshi, Gurunath M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical synthesis Diketones Substitutes Substrates Triflic acid
Online-Zugang:	Volltext
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