Dynamic energy budget approach to evaluate antibiotic effects on biofilms

•Hybrid dynamic energy budget models describe antibiotic effects on biofilms.•Experimentally measured death rates are reproduced numerically.•Spatial variations observed in the distribution of cell types are recreated.•Qualitative predictions in agreement with experimental observations follow.•Antib...

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Veröffentlicht in:	Communications in nonlinear science & numerical simulation 2018-01, Vol.54, p.70-83
Hauptverfasser:	Birnir, Bjorn, Carpio, Ana, Cebrián, Elena, Vidal, Perfecto
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotic Antibiotics Bacterial biofilm Biofilms Dynamic energy budget Energy budget Hypothesis testing Mathematical models Metabolism Numerical simulation Polymers Simulation Survival
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