Metal ions affect the formation and stability of amyloid β aggregates at multiple length scales

Amyloid β (Aβ) aggregates, which are a hallmark for neurodegenerative disease, are formed through a self-assembly process such as aggregation of Aβ peptide chains. This aggregation process depends on the solvent conditions under which the proteins are aggregated. Nevertheless, the underlying mechani...

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Veröffentlicht in:	Physical chemistry chemical physics : PCCP 2018, Vol.20 (13), p.8951-8961
Hauptverfasser:	Lee, Myeongsang, Kim, Jae In, Na, Sungsoo, Eom, Kilho
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglomeration Aggregates Copper Hydrogen bonds Ions Metal ions Metals Neurological diseases Oligomers Proteins Self-assembly Stability Zinc
Online-Zugang:	Volltext
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