A case report of recurrent respiratory papillomatosis progressed into a loco-regionally advanced laryngeal carcinoma

In this article, we present the clinical course of a patient who had more than 30 operations for recurrent laryngeal papillomatosis associated with HPV type 11 infection, and who was diagnosed with a laryngeal squamous cell carcinoma at the age of 34 years. Other risk factors such as smoking or hereditary tendency to malignant tumors were associate in this case. It is known that Recurrent respiratory papillomatosis (RRP) has the potential to suffer malignant transformation. The risk of cancer must be considered in all cases of laryngeal papillomatosis, requiring special attention especially in cases with multiple relapses.