Orthogonal 19F‐Labeling for Solid‐State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes

Peptaibols are promising drug candidates in view of their interference with cellular membranes. Knowledge of their lipid interactions and membrane‐bound structure is needed to understand their activity and should be, in principle, accessible by solid‐state NMR spectroscopy. However, their unusual am...

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Veröffentlicht in:Chemistry : a European journal 2018-03, Vol.24 (17), p.4328-4335
Hauptverfasser: Grage, Stephan L., Kara, Sezgin, Bordessa, Andrea, Doan, Véronique, Rizzolo, Fabio, Putzu, Marina, Kubař, Tomáš, Papini, Anna Maria, Chaume, Grégory, Brigaud, Thierry, Afonin, Sergii, Ulrich, Anne S.
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Sprache:eng
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