False discovery control with p-value weighting

We present a method for multiple hypothesis testing that maintains control of the false discovery rate while incorporating prior information about the hypotheses. The prior information takes the form of p-value weights. If the assignment of weights is positively associated with the null hypotheses b...

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Veröffentlicht in:	Biometrika 2006-09, Vol.93 (3), p.509-524
Hauptverfasser:	Genovese, Christopher R., Roeder, Kathryn, Wasserman, Larry
Format:	Artikel
Sprache:	eng
Schlagworte:	A priori knowledge Applications Biology, psychology, social sciences Epidemiology Error rates Exact sciences and technology False discovery rate General topics Genomes Hypotheses Hypothesis testing Magnetic resonance imaging Mathematical procedures Mathematics Medical genetics Methods Multiple testing Null hypothesis P values Power Probability and statistics Probability distribution Probability distributions Random variables Sciences and techniques of general use Statistical analysis Statistics Studies Term weighting
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