LONG-TERM FOLLOW UP OF ACUTE HEART FAILURE PATIENTS UNDERWENT LEVOSIMENDAN INFUSION: IDENTIFICATION OF RESPONDERS AND NON-RESPONDERS BY USING HLM CLASSIFICATION

Background Levosimendan (Levo) reduces mortality in Acute Heart Failure (AHF) that determines involvement of other organs beyond heart; similar to TNM used in oncology, we proposed HLM staging system to assess prognosis of HF patients evaluating heart damage (H), lung involvement (L) and malfunction...

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Veröffentlicht in:Journal of the American College of Cardiology 2018-03, Vol.71 (11), p.A821-A821
Hauptverfasser: Alfarano, Maria, Severino, Paolo, Mancini, Ilaria, Pucci, Mariateresa, Pagliaroli, Elisa, Straito, Martina, Ferrari, Ilaria, Peroni, Stefano, Calcagno, Simone, Fusto, Antonio, Mancone, Massimo, Fedele, Francesco
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container_end_page A821
container_issue 11
container_start_page A821
container_title Journal of the American College of Cardiology
container_volume 71
creator Alfarano, Maria
Severino, Paolo
Mancini, Ilaria
Pucci, Mariateresa
Pagliaroli, Elisa
Straito, Martina
Ferrari, Ilaria
Peroni, Stefano
Calcagno, Simone
Fusto, Antonio
Mancone, Massimo
Fedele, Francesco
description Background Levosimendan (Levo) reduces mortality in Acute Heart Failure (AHF) that determines involvement of other organs beyond heart; similar to TNM used in oncology, we proposed HLM staging system to assess prognosis of HF patients evaluating heart damage (H), lung involvement (L) and malfunction (M) of peripheral organs. The aim is to evaluate the outcomes of Levo infusion in AHF patients and identify the predictors of cardiac mortality and rehospitalization for major cardiovascular and cerebrovascular events (MACCE) by using HLM classification Methods All 300 AHF enrolled patients received 24h Levo iv infusion (0.05- 0.2 μg/kg/min, no bolus) in addition to standard therapy.
doi_str_mv 10.1016/S0735-1097(18)31362-7
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source Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Cardiology
Cerebrovascular system
Heart diseases
Heart failure
Mortality
title LONG-TERM FOLLOW UP OF ACUTE HEART FAILURE PATIENTS UNDERWENT LEVOSIMENDAN INFUSION: IDENTIFICATION OF RESPONDERS AND NON-RESPONDERS BY USING HLM CLASSIFICATION
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