Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis)

The herbicide atrazine is one of the most commonly applied pesticides in the world. As a result, atrazine is the most commonly detected pesticide contaminant of ground, surface, and drinking water. Atrazine is also a potent endocrine disruptor that is active at low, ecologically relevant concentrati...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2010-03, Vol.107 (10), p.4612-4617
Hauptverfasser:	Hayes, Tyrone B, Khoury, Vicky, Narayan, Anne, Nazir, Mariam, Park, Andrew, Brown, Travis, Adame, Lillian, Chan, Elton, Buchholz, Daniel, Stueve, Theresa, Gallipeau, Sherrie
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphibians Analysis of Variance Animal glands Animal reproduction Animals Anura atrazine Atrazine - toxicity Biological Sciences Breeding Castration chemical castration Contamination endocrine-disrupting chemicals Environmental Pollutants - toxicity fecundity Female Female animals feminization Feminization - blood Feminization - chemically induced Feminization - physiopathology Fertility - drug effects Frogs Herbicides Herbicides - toxicity Larva - drug effects Larva - physiology Larynx - drug effects Larynx - pathology Male Male animals male fertility males Mating behavior reproductive toxicology Sex Differentiation - drug effects sex reversal Sexual Behavior, Animal - drug effects sexual reproduction spermatogenesis Spermatogenesis - drug effects Spermatozoa Testis - drug effects Testis - pathology Testosterone Testosterone - blood Water Xenopus laevis Xenopus laevis - physiology
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