Cytokine-induced memory-like natural killer cells

The mammalian immune response to infection is mediated by 2 broad arms, the innate and adaptive immune systems. Innate immune cells are a first-line defense against pathogens and are thought to respond consistently to infection, regardless of previous exposure, i.e., they do not exhibit memory of pr...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2009-02, Vol.106 (6), p.1915-1919
Hauptverfasser:	Cooper, Megan A, Elliott, Julie M, Keyel, Peter A, Yang, Liping, Carrero, Javier A, Yokoyama, Wayne M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive transfer Animals Antigens Biological Sciences Cells Cytokines Cytokines - immunology Granzymes - analysis Immune system Immunity, Innate Immunologic Memory Infections Innate immunity Interferon-gamma - biosynthesis Killer Cells, Natural - immunology Killer Cells, Natural - transplantation Lymphocyte Activation - immunology Lymphocyte Transfusion Lymphocytes Memory Mice Mice, Knockout Natural killer cells Pathogens Receptors
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