Characterization of the 1918 "Spanish" Influenza Virus Neuraminidase Gene

The "Spanish" influenza pandemic of 1918 was characterized by exceptionally high mortality, especially among young adults. The surface proteins of influenza viruses, hemagglutinin and neuraminidase, play important roles in virulence, host specificity, and the human immune response. The com...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2000-06, Vol.97 (12), p.6785-6790
Hauptverfasser:	Reid, Ann H., Fanning, Thomas G., Janczewski, Thomas A., Taubenberger, Jeffery K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Active sites Adult Amino Acid Sequence Amino acids Base Sequence Biological Sciences Catalytic Domain Epidemics Female Genes Glycosylation H1N1 subtype influenza A virus History Humans Influenza Influenza A virus - classification Influenza A virus - enzymology Influenza A virus - genetics Influenza virus Male Microbiology Molecular Sequence Data Neuraminidase - chemistry Neuraminidase - genetics Nucleotides Pandemics Pathology Phylogenetics Phylogeny Spain Swine Virulence Viruses
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