A tenascin-C aptamer indentified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment

The targeting of molecular repertoires to complex systems rather than biochemically pure entities is an accessible approach that can identify proteins of biological interest. We have probed antigens presented by a monolayer of tumor cells for their ability to interact with a pool of aptamers. A glio...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2003-12, Vol.100 (26), p.15416
Hauptverfasser: Daniels, Dion A, Chen, Hang, Hicke, Brian J, Swiderek, Kristine M, Gold, Larry
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Sprache:eng
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