Antitumor Polyketide Biosynthesis by an Uncultivated Bacterial Symbiont of the Marine Sponge Theonella swinhoei

Bacterial symbionts have long been suspected to be the true producers of many drug candidates isolated from marine invertebrates. Sponges, the most important marine source of biologically active natural products, have been frequently hypothesized to contain compounds of bacterial origin. This symbio...

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