Imaging of amyloid [beta] in Alzheimer's disease with ^sup 18^F-BAY94-9172, a novel PET tracer: proof of mechanism

Amyloid-beta (Abeta) plaque formation is a hallmark of Alzheimer's disease (AD) and precedes the onset of dementia. Abeta imaging should allow earlier diagnosis, but clinical application is hindered by the short decay half-life of current Abeta-specific ligands. (18)F-BAY94-9172 is an Abeta lig...

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Veröffentlicht in:	Lancet neurology 2008-02, Vol.7 (2), p.129
Hauptverfasser:	Rowe, Christopher C, Ackerman, Uwe, Browne, William, Mulligan, Rachel, Pike, Kerryn L, O'Keefe, Graeme, Tochon-Danguy, Henry, Chan, Gordon, Berlangieri, Salvatore U, Jones, Gareth, Dickinson-Rowe, Kerryn L, Kung, Hank P, Zhang, Wei, Kung, Mei Ping, Skovronsky, Daniel, Dyrks, Thomas, Holl, Gerhard, Krause, Sabine, Friebe, Matthias, Lehman, Lutz, Lindemann, Stefanie, Dinkelborg, Ludger M, Masters, Colin L, Villemagne, Victor L
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Brain research Clinical medicine Cognitive ability Dementia Disease Ligands Memory Patients
Online-Zugang:	Volltext
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