Regulation of Plant Growth by Cytokinin
Cytokinins are a class of plant-specific hormones that play a central role during the cell cycle and influence numerous developmental programs. Because of the lack of biosynthetic and signaling mutants, the regulatory roles of cytokinins are not well understood. We genetically engineered cytokinin o...
Gespeichert in:
| Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 2001-08, Vol.98 (18), p.10487-10492 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 10492 |
|---|---|
| container_issue | 18 |
| container_start_page | 10487 |
| container_title | Proceedings of the National Academy of Sciences - PNAS |
| container_volume | 98 |
| creator | Werner, Tomáš Motyka, Václav Strnad, Miroslav Schmülling, Thomas |
| description | Cytokinins are a class of plant-specific hormones that play a central role during the cell cycle and influence numerous developmental programs. Because of the lack of biosynthetic and signaling mutants, the regulatory roles of cytokinins are not well understood. We genetically engineered cytokinin oxidase expression in transgenic tobacco plants to reduce their endogenous cytokinin content. Cytokinin-deficient plants developed stunted shoots with smaller apical meristems. The plastochrone was prolonged, and leaf cell production was only 3-4% that of wild type, indicating an absolute requirement of cytokinins for leaf growth. In contrast, root meristems of transgenic plants were enlarged and gave rise to faster growing and more branched roots. These results suggest that cytokinins are an important regulatory factor of plant meristem activity and morphogenesis, with opposing roles in shoots and roots. |
| doi_str_mv | 10.1073/pnas.171304098 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_journals_201382386</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>3056555</jstor_id><sourcerecordid>3056555</sourcerecordid><originalsourceid>FETCH-LOGICAL-c586t-3852109d2cde2ac4726bfa5ec487a0d6ed59d514b942e7476927e0f7c4a65df13</originalsourceid><addsrcrecordid>eNp90EtrGzEUBWBRGhLnse2qtEMWSTbjXGn0hG6CyQsMKaVdC3lG44w7HrmSJon_feTYcdssAgIt9B1x70HoE4YhBlGcLzoThljgAigo-QENMCicc6rgIxoAEJFLSuge2g9hBgCKSdhFexgzSEQN0OkPO-1bExvXZa7Ovremi9m1d4_xPpsss9Eyut9N13SHaKc2bbBHm_sA_bq6_Dm6ycd317eji3FeMsljXkhG0gQVKStLTEkF4ZPaMFtSKQxU3FZMVQzTiaLECiq4IsJCLUpqOKtqXBygb-t_F_1kbqvSdtGbVi98Mzd-qZ1p9P8vXXOvp-5BM66kSPGTTdy7P70NUc-bUNo2rWVdHzQWUnEpeYLHb-DM9b5Lq2kCuJCkeEHDNSq9C8HbejsHBr2qX6_q19v6U-DLv9P_5Zu-EzjbgFXw9VlJjdOBVJKu-7aN9ikm-vV9msTntZiF6PyWFMA4Y6x4BpoCoc0</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>201382386</pqid></control><display><type>article</type><title>Regulation of Plant Growth by Cytokinin</title><source>MEDLINE</source><source>JSTOR Archive Collection A-Z Listing</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>Free Full-Text Journals in Chemistry</source><creator>Werner, Tomáš ; Motyka, Václav ; Strnad, Miroslav ; Schmülling, Thomas</creator><creatorcontrib>Werner, Tomáš ; Motyka, Václav ; Strnad, Miroslav ; Schmülling, Thomas</creatorcontrib><description>Cytokinins are a class of plant-specific hormones that play a central role during the cell cycle and influence numerous developmental programs. Because of the lack of biosynthetic and signaling mutants, the regulatory roles of cytokinins are not well understood. We genetically engineered cytokinin oxidase expression in transgenic tobacco plants to reduce their endogenous cytokinin content. Cytokinin-deficient plants developed stunted shoots with smaller apical meristems. The plastochrone was prolonged, and leaf cell production was only 3-4% that of wild type, indicating an absolute requirement of cytokinins for leaf growth. In contrast, root meristems of transgenic plants were enlarged and gave rise to faster growing and more branched roots. These results suggest that cytokinins are an important regulatory factor of plant meristem activity and morphogenesis, with opposing roles in shoots and roots.</description><identifier>ISSN: 0027-8424</identifier><identifier>EISSN: 1091-6490</identifier><identifier>DOI: 10.1073/pnas.171304098</identifier><identifier>PMID: 11504909</identifier><language>eng</language><publisher>United States: National Academy of Sciences</publisher><subject>Biological Sciences ; Biology ; Cell growth ; cytokinin oxidase ; Cytokinins ; Cytokinins - genetics ; Cytokinins - physiology ; Epidermal cells ; Flowers & plants ; Genes ; Genes, Plant ; Hormones ; Leaves ; Meristem - growth & development ; Models, Biological ; Nicotiana ; Nicotiana - genetics ; Nicotiana - growth & development ; Nicotiana - physiology ; Oxidases ; Oxidoreductases - genetics ; Oxidoreductases - physiology ; Phenotype ; Plant growth ; Plant growth regulators ; Plant roots ; Plant Roots - growth & development ; Plant Shoots - growth & development ; Plants ; Plants, Genetically Modified ; Plants, Toxic ; Stem cells ; Transgenic plants</subject><ispartof>Proceedings of the National Academy of Sciences - PNAS, 2001-08, Vol.98 (18), p.10487-10492</ispartof><rights>Copyright 1993-2001 National Academy of Sciences of the United States of America</rights><rights>Copyright National Academy of Sciences Aug 28, 2001</rights><rights>Copyright © 2001, The National Academy of Sciences 2001</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c586t-3852109d2cde2ac4726bfa5ec487a0d6ed59d514b942e7476927e0f7c4a65df13</citedby><cites>FETCH-LOGICAL-c586t-3852109d2cde2ac4726bfa5ec487a0d6ed59d514b942e7476927e0f7c4a65df13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://www.pnas.org/content/98/18.cover.gif</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/3056555$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/3056555$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,727,780,784,803,885,27924,27925,53791,53793,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11504909$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Werner, Tomáš</creatorcontrib><creatorcontrib>Motyka, Václav</creatorcontrib><creatorcontrib>Strnad, Miroslav</creatorcontrib><creatorcontrib>Schmülling, Thomas</creatorcontrib><title>Regulation of Plant Growth by Cytokinin</title><title>Proceedings of the National Academy of Sciences - PNAS</title><addtitle>Proc Natl Acad Sci U S A</addtitle><description>Cytokinins are a class of plant-specific hormones that play a central role during the cell cycle and influence numerous developmental programs. Because of the lack of biosynthetic and signaling mutants, the regulatory roles of cytokinins are not well understood. We genetically engineered cytokinin oxidase expression in transgenic tobacco plants to reduce their endogenous cytokinin content. Cytokinin-deficient plants developed stunted shoots with smaller apical meristems. The plastochrone was prolonged, and leaf cell production was only 3-4% that of wild type, indicating an absolute requirement of cytokinins for leaf growth. In contrast, root meristems of transgenic plants were enlarged and gave rise to faster growing and more branched roots. These results suggest that cytokinins are an important regulatory factor of plant meristem activity and morphogenesis, with opposing roles in shoots and roots.</description><subject>Biological Sciences</subject><subject>Biology</subject><subject>Cell growth</subject><subject>cytokinin oxidase</subject><subject>Cytokinins</subject><subject>Cytokinins - genetics</subject><subject>Cytokinins - physiology</subject><subject>Epidermal cells</subject><subject>Flowers & plants</subject><subject>Genes</subject><subject>Genes, Plant</subject><subject>Hormones</subject><subject>Leaves</subject><subject>Meristem - growth & development</subject><subject>Models, Biological</subject><subject>Nicotiana</subject><subject>Nicotiana - genetics</subject><subject>Nicotiana - growth & development</subject><subject>Nicotiana - physiology</subject><subject>Oxidases</subject><subject>Oxidoreductases - genetics</subject><subject>Oxidoreductases - physiology</subject><subject>Phenotype</subject><subject>Plant growth</subject><subject>Plant growth regulators</subject><subject>Plant roots</subject><subject>Plant Roots - growth & development</subject><subject>Plant Shoots - growth & development</subject><subject>Plants</subject><subject>Plants, Genetically Modified</subject><subject>Plants, Toxic</subject><subject>Stem cells</subject><subject>Transgenic plants</subject><issn>0027-8424</issn><issn>1091-6490</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90EtrGzEUBWBRGhLnse2qtEMWSTbjXGn0hG6CyQsMKaVdC3lG44w7HrmSJon_feTYcdssAgIt9B1x70HoE4YhBlGcLzoThljgAigo-QENMCicc6rgIxoAEJFLSuge2g9hBgCKSdhFexgzSEQN0OkPO-1bExvXZa7Ovremi9m1d4_xPpsss9Eyut9N13SHaKc2bbBHm_sA_bq6_Dm6ycd317eji3FeMsljXkhG0gQVKStLTEkF4ZPaMFtSKQxU3FZMVQzTiaLECiq4IsJCLUpqOKtqXBygb-t_F_1kbqvSdtGbVi98Mzd-qZ1p9P8vXXOvp-5BM66kSPGTTdy7P70NUc-bUNo2rWVdHzQWUnEpeYLHb-DM9b5Lq2kCuJCkeEHDNSq9C8HbejsHBr2qX6_q19v6U-DLv9P_5Zu-EzjbgFXw9VlJjdOBVJKu-7aN9ikm-vV9msTntZiF6PyWFMA4Y6x4BpoCoc0</recordid><startdate>20010828</startdate><enddate>20010828</enddate><creator>Werner, Tomáš</creator><creator>Motyka, Václav</creator><creator>Strnad, Miroslav</creator><creator>Schmülling, Thomas</creator><general>National Academy of Sciences</general><general>National Acad Sciences</general><general>The National Academy of Sciences</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>5PM</scope></search><sort><creationdate>20010828</creationdate><title>Regulation of Plant Growth by Cytokinin</title><author>Werner, Tomáš ; Motyka, Václav ; Strnad, Miroslav ; Schmülling, Thomas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c586t-3852109d2cde2ac4726bfa5ec487a0d6ed59d514b942e7476927e0f7c4a65df13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Biological Sciences</topic><topic>Biology</topic><topic>Cell growth</topic><topic>cytokinin oxidase</topic><topic>Cytokinins</topic><topic>Cytokinins - genetics</topic><topic>Cytokinins - physiology</topic><topic>Epidermal cells</topic><topic>Flowers & plants</topic><topic>Genes</topic><topic>Genes, Plant</topic><topic>Hormones</topic><topic>Leaves</topic><topic>Meristem - growth & development</topic><topic>Models, Biological</topic><topic>Nicotiana</topic><topic>Nicotiana - genetics</topic><topic>Nicotiana - growth & development</topic><topic>Nicotiana - physiology</topic><topic>Oxidases</topic><topic>Oxidoreductases - genetics</topic><topic>Oxidoreductases - physiology</topic><topic>Phenotype</topic><topic>Plant growth</topic><topic>Plant growth regulators</topic><topic>Plant roots</topic><topic>Plant Roots - growth & development</topic><topic>Plant Shoots - growth & development</topic><topic>Plants</topic><topic>Plants, Genetically Modified</topic><topic>Plants, Toxic</topic><topic>Stem cells</topic><topic>Transgenic plants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Werner, Tomáš</creatorcontrib><creatorcontrib>Motyka, Václav</creatorcontrib><creatorcontrib>Strnad, Miroslav</creatorcontrib><creatorcontrib>Schmülling, Thomas</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Werner, Tomáš</au><au>Motyka, Václav</au><au>Strnad, Miroslav</au><au>Schmülling, Thomas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Regulation of Plant Growth by Cytokinin</atitle><jtitle>Proceedings of the National Academy of Sciences - PNAS</jtitle><addtitle>Proc Natl Acad Sci U S A</addtitle><date>2001-08-28</date><risdate>2001</risdate><volume>98</volume><issue>18</issue><spage>10487</spage><epage>10492</epage><pages>10487-10492</pages><issn>0027-8424</issn><eissn>1091-6490</eissn><abstract>Cytokinins are a class of plant-specific hormones that play a central role during the cell cycle and influence numerous developmental programs. Because of the lack of biosynthetic and signaling mutants, the regulatory roles of cytokinins are not well understood. We genetically engineered cytokinin oxidase expression in transgenic tobacco plants to reduce their endogenous cytokinin content. Cytokinin-deficient plants developed stunted shoots with smaller apical meristems. The plastochrone was prolonged, and leaf cell production was only 3-4% that of wild type, indicating an absolute requirement of cytokinins for leaf growth. In contrast, root meristems of transgenic plants were enlarged and gave rise to faster growing and more branched roots. These results suggest that cytokinins are an important regulatory factor of plant meristem activity and morphogenesis, with opposing roles in shoots and roots.</abstract><cop>United States</cop><pub>National Academy of Sciences</pub><pmid>11504909</pmid><doi>10.1073/pnas.171304098</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0027-8424 |
| ispartof | Proceedings of the National Academy of Sciences - PNAS, 2001-08, Vol.98 (18), p.10487-10492 |
| issn | 0027-8424 1091-6490 |
| language | eng |
| recordid | cdi_proquest_journals_201382386 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | Biological Sciences Biology Cell growth cytokinin oxidase Cytokinins Cytokinins - genetics Cytokinins - physiology Epidermal cells Flowers & plants Genes Genes, Plant Hormones Leaves Meristem - growth & development Models, Biological Nicotiana Nicotiana - genetics Nicotiana - growth & development Nicotiana - physiology Oxidases Oxidoreductases - genetics Oxidoreductases - physiology Phenotype Plant growth Plant growth regulators Plant roots Plant Roots - growth & development Plant Shoots - growth & development Plants Plants, Genetically Modified Plants, Toxic Stem cells Transgenic plants |
| title | Regulation of Plant Growth by Cytokinin |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-22T14%3A13%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Regulation%20of%20Plant%20Growth%20by%20Cytokinin&rft.jtitle=Proceedings%20of%20the%20National%20Academy%20of%20Sciences%20-%20PNAS&rft.au=Werner,%20Tom%C3%A1%C5%A1&rft.date=2001-08-28&rft.volume=98&rft.issue=18&rft.spage=10487&rft.epage=10492&rft.pages=10487-10492&rft.issn=0027-8424&rft.eissn=1091-6490&rft_id=info:doi/10.1073/pnas.171304098&rft_dat=%3Cjstor_proqu%3E3056555%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=201382386&rft_id=info:pmid/11504909&rft_jstor_id=3056555&rfr_iscdi=true |