The Crucial Role of Polymorphonuclear Leukocytes in Resistance to Salmonella dublin Infections in Genetically Susceptible and Resistant Mice

Macrophages are considered to be the mediators of resistance to extra-intestinal Salmonella infections. Nevertheless, the initial cellular response to Salmonella infections consists primarily of polymorphonuclear leukocytes (PMN). To determine whether PMN serve an important function for the infected...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1998-06, Vol.95 (13), p.7676-7681
Hauptverfasser:	Vassiloyanakopoulos, Antonis P., Okamoto, Sharon, Fierer, Joshua
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Antibodies, Monoclonal - immunology Bacteria Biological Sciences Carrier Proteins - genetics Carrier Proteins - immunology Cation Transport Proteins Genetic Predisposition to Disease Genetics Humans Immunity, Innate - genetics Infections Leukocytes Liver Macrophages Macrophages - immunology Membrane Proteins - genetics Membrane Proteins - immunology Mice Mice, Inbred BALB C Mice, Inbred DBA Neutropenia Neutropenia - complications Neutropenia - immunology Neutrophils Neutrophils - immunology Plasmids Rats Salmonella Salmonella Infections, Animal - complications Salmonella Infections, Animal - genetics Salmonella Infections, Animal - immunology Spleen Virulence
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