Use of Nanocrystalline ZnO as an Efficient and Reusable Catalyst for a One-Pot, Three-Component Synthesis of 6-Chloro- and 5,7-Dichloro-4-Hydroxy-3-[Aryl (Piperidin-1-yl)Methyl]Quinolin-2(1H)-Ones in Water
A one-pot, green, efficient and facile procedure was applied for the preparation of a series of 4-hydroxy-3-[aryl(piperidin-1-yl)methyl] quinolin-2(1H)-ones via the reaction of 6-chloro-4- hydroxyquinoline-2(1H)-one 1 and/or 5,7-dichloro-4-hydroxyquinoline-2(1H)-one 2, piperidine and aromatic aldehy...
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| Veröffentlicht in: | Journal of chemical research 2018-02, Vol.42 (2), p.116-120 |
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| creator | Astaneh, H. R. Haghjoo Rufchahi, E. O. Moradi |
| description | A one-pot, green, efficient and facile procedure was applied for the preparation of a series of 4-hydroxy-3-[aryl(piperidin-1-yl)methyl] quinolin-2(1H)-ones via the reaction of 6-chloro-4- hydroxyquinoline-2(1H)-one 1 and/or 5,7-dichloro-4-hydroxyquinoline-2(1H)-one 2, piperidine and aromatic aldehydes in water in the presence of nanocrystalline ZnO under reflux conditions. The desired products were obtained in satisfactory yields. The nanocrystalline ZnO can be separated and reused at least up to three times with almost the same catalytic activity. |
| doi_str_mv | 10.3184/174751918X15192990175864 |
| format | Article |
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| ispartof | Journal of chemical research, 2018-02, Vol.42 (2), p.116-120 |
| issn | 1747-5198 2047-6507 |
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| source | Sage Journals GOLD Open Access 2024 |
| subjects | Aldehydes Aromatic compounds Catalysis Catalytic activity Chemical synthesis Hydroxyquinoline Nanocrystals Piperidine Reusable components Zinc oxide |
| title | Use of Nanocrystalline ZnO as an Efficient and Reusable Catalyst for a One-Pot, Three-Component Synthesis of 6-Chloro- and 5,7-Dichloro-4-Hydroxy-3-[Aryl (Piperidin-1-yl)Methyl]Quinolin-2(1H)-Ones in Water |
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