Detecting Conserved Regulatory Elements with the Model Genome of the Japanese Puffer Fish, Fugu rubripes

Comparative vertebrate genome sequencing offers a powerful method for detecting conserved regulatory sequences. We propose that the compact genome of the teleost Fugu rubripes is well suited for this purpose. The evolutionary distance of teleosts from other vertebrates offers the maximum stringency...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1995-02, Vol.92 (5), p.1684-1688
Hauptverfasser:	Aparicio, Samuel, Morrison, Alastair, Gould, Alex, Gilthorpe, Jonathan, Chaudhuri, Chitrita, Rigby, Peter, Krumlauf, Robb, Brenner, Sydney
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteriophages Base Sequence Cloning, Molecular DNA Embryos Enhancer Elements, Genetic Evolution Fish Fishes, Poisonous - genetics Fugu rubripes Gene Expression Regulation, Developmental Genes Genes, Homeobox Genetics Genomes Introns Marine Mice Mice, Inbred C57BL Mice, Inbred CBA Mice, Transgenic Molecular Sequence Data Nervous System - embryology Nervous System - metabolism Regulatory Sequences, Nucleic Acid RNA, Messenger - genetics Sequence Alignment Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid Transgenic animals Vertebrates
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