Emergence of a new epidemic/epizootic Venezuelan equine encephalitis virus in South America

One of the most important questions in arbovirology concerns the origin of epidemic Venezuelan equine encephalitis (VEE) viruses; these viruses caused periodic, extensive epidemics/epizootics in the Americas from 1938-1973 (reaching the United States in 1971) but had recently been presumed extinct....

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1995-06, Vol.92 (12), p.5278-5281
Hauptverfasser: Rico-Hesse, R. (Yale University School of Medicine, New Haven, CT.), Weaver, S.C, Siger, J. de, Medina, G, Salas, R.A
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Sprache:eng
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Zusammenfassung:One of the most important questions in arbovirology concerns the origin of epidemic Venezuelan equine encephalitis (VEE) viruses; these viruses caused periodic, extensive epidemics/epizootics in the Americas from 1938-1973 (reaching the United States in 1971) but had recently been presumed extinct. We have documented the 1992 emergence of a new epidemic/epizootic VEE virus in Venezuela. Phylogenetic analysis of strains isolated during two outbreaks indicated that the new epidemic/epizootic virus(es) evolved recently from an enzootic VEE virus in northern South America. These results suggest continued emergence of epizootic VEE viruses; surveillance of enzootic viruses and routine vaccination of equines should therefore be resumed.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.92.12.5278