Nonlinear Protein Degradation and the Function of Genetic Circuits

The functions of most genetic circuits require a sufficient degree of cooperativity in the circuit components. Although mechanisms of cooperativity have been studied most extensively in the context of transcriptional initiation control, cooperativity from other processes involved in the operation of...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2005-07, Vol.102 (27), p.9559-9564
Hauptverfasser:	Buchler, Nicolas E., Gerland, Ulrich, Hwa, Terence, Varshavsky, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Bacteria - genetics Biological Sciences Dimerization Dimers Evolutionary genetics Gene Expression Regulation Genes Genetics Messenger RNA Models, Biological Molecular biology Molecular genetics Molecules Monomers Multiprotein Complexes - metabolism Protein Engineering - methods Protein Subunits - metabolism Proteins Proteins - metabolism Transcription Factors - metabolism
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