Evaluation of the Influence of Three Newly Developed Bispyridinium Anti‐nicotinic Compounds (MB408, MB442, MB444) on the Efficacy of Antidotal Treatment of Nerve Agent Poisoning in Mice

The influence of three newly developed bispyridinium antinicotinic compounds (the non‐oximes MB408, MB442 and MB444) on the therapeutic efficacy of a standard antidotal treatment (atropine in combination with an oxime) of acute poisoning by the organophosphorus nerve agents tabun and soman was studi...

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Veröffentlicht in:	Basic & clinical pharmacology & toxicology 2018-04, Vol.122 (4), p.429-435
Hauptverfasser:	Kassa, Jiri, Timperley, Christopher M., Bird, Mike, Williams, Rebecca L., Green, A. Christopher, Tattersall, John E. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Atropine Biological & chemical weapons Effectiveness Mice Nerve agents Oximes Poisoning Pyridinium Reagents Soman Tabun
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