SEL 1L nucleates a protein complex required for dislocation of misfolded glycoproteins

Membrane and secretory proteins that fail to pass quality control in the endoplasmic reticulum are discharged into the cytosol and degraded by the proteasome. Many of the mammalian components involved in this process remain to be identified. We performed a biochemical search for proteins that intera...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2008-08, Vol.105 (34), p.12325
Hauptverfasser:	Mueller, Britta, Klemm, Elizabeth J, Spooner, Eric, Claessen, Jasper H, Ploegh, Hidde L
Format:	Artikel
Sprache:	eng
Schlagworte:	Glycoproteins Mammals Membranes Mutation Protein folding Proteomics
Online-Zugang:	Volltext
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