The Molecular Program Induced in T Cells Undergoing Homeostatic Proliferation

Naïve T cells proliferate independently of cognate antigen when introduced into lymphopenic hosts. Lymphopenia-induced proliferation depends on low-affinity MHC/self-peptide complexes and on IL-7. To elucidate the intracellular signals mediating this proliferation, we analyzed changes in gene expres...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2004-11, Vol.101 (48), p.16885-16890
Hauptverfasser:	Goldrath, Ananda W., Luckey, C. John, Park, Richard, Benoist, Christophe, Mathis, Diane
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Base Sequence Biological Sciences Cell Division - immunology Cell growth Datasets DNA Probes Female Gene expression Gene Expression Profiling Genes Homeostasis Immunology Memory Mice Mice, Inbred C57BL RNA Stem cells T cell antigen receptors T cell receptors T lymphocytes T-Lymphocytes - cytology T-Lymphocytes - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!