The Src homology 2 domain of the protein-tyrosine kinase p56(lck) mediates both intermolecular and intramolecular interactions

The Src homology 2 domain of the protein-tyrosine kinase p56(lck) mediates both intermolecular and intramolecular interactions

It is demonstrated that purified recombinant Src homology 2 (SH2) and HSH3/SH2 domains of p56lck can mediate intermolecular interactions with a number of tyrosinephosphorylated proteins.

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1993-11, Vol.90 (21), p.10285
Hauptverfasser: Amrein, Kurt E, Panholzer, Baerbel, Flint, Nicholas A, Bannwarth, Willi, Burn, Paul
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Biochemistry
Proteins
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container_end_page
container_issue 21
container_start_page 10285
container_title Proceedings of the National Academy of Sciences - PNAS
container_volume 90
creator Amrein, Kurt E
Panholzer, Baerbel
Flint, Nicholas A
Bannwarth, Willi
Burn, Paul
description It is demonstrated that purified recombinant Src homology 2 (SH2) and HSH3/SH2 domains of p56lck can mediate intermolecular interactions with a number of tyrosinephosphorylated proteins.
doi_str_mv 10.1073/pnas.90.21.10285
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source JSTOR Archive Collection A-Z Listing; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry
subjects Biochemistry
Proteins
title The Src homology 2 domain of the protein-tyrosine kinase p56(lck) mediates both intermolecular and intramolecular interactions
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