Insulin receptor substrate 1 mediates insulin and insuilin-like growth factor I-stimulated maturation of Xenopus oocytes

Insulin receptor substrate 1 mediates insulin and insuilin-like growth factor I-stimulated maturation of Xenopus oocytes

Insulin and insulin-like growth factor I (IGF-I) initiate cellular functions by activating their homologous tyrosine kinase receptors. Research findings demonstrate that insulin receptor substrate-1 (IRS-1) serves a critical role in linking IGF-I and insulin to their final cellular responses.

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1993-06, Vol.90 (11), p.5172
Hauptverfasser: Chuang, Lee-Ming, Myers, Martin G, Seidner, Glen A, Birnbaum, Morris J
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Sprache:eng
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Cellular biology
Insulin
Medical research
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container_issue 11
container_start_page 5172
container_title Proceedings of the National Academy of Sciences - PNAS
container_volume 90
creator Chuang, Lee-Ming
Myers, Martin G
Seidner, Glen A
Birnbaum, Morris J
description Insulin and insulin-like growth factor I (IGF-I) initiate cellular functions by activating their homologous tyrosine kinase receptors. Research findings demonstrate that insulin receptor substrate-1 (IRS-1) serves a critical role in linking IGF-I and insulin to their final cellular responses.
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ispartof Proceedings of the National Academy of Sciences - PNAS, 1993-06, Vol.90 (11), p.5172
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1091-6490
language eng
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source JSTOR Archive Collection A-Z Listing; PubMed Central; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry
subjects Cellular biology
Insulin
Medical research
title Insulin receptor substrate 1 mediates insulin and insuilin-like growth factor I-stimulated maturation of Xenopus oocytes
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