Stable Growth Transformation of Human T Lymphocytes by Herpesvirus saimiri

Herpesvirus saimiri induces T-cell lymphomas in various species of New World monkeys and in rabbits, and it is able to immortalize monkey T lymphocytes in vitro. Sequences responsible for these effects have been localized to a region of the genome that varies significantly among the virus subgroups...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1992-04, Vol.89 (7), p.3116-3119
Hauptverfasser:	Biesinger, Brigitte, Muller-Fleckenstein, Ingrid, Simmer, Birgit, Lang, Gerlinde, Wittmann, Sabine, Platzer, Erich, Desrosiers, Ronald C., Fleckenstein, Bernhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Differentiation, T-Lymphocyte - analysis Blood Blood cells Cell Division Cell lines Cell Transformation, Viral Cellular biology DNA, Viral - analysis Flow Cytometry Herpes viruses Herpesvirus 2, Saimiriine Herpesvirus saimiri Humans Immunity (Disease) In Vitro Techniques K562 cells Kidney cells Leukocytes Lymphocytes Medical research Saimiriine herpesvirus 2 T lymphocytes T-Lymphocytes - cytology T-Lymphocytes - immunology T-Lymphocytes - microbiology Viruses
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