The Effect of Ubiquitin Like Protein-Proteasome System on the Drug Resistance of Isoniazid Mono-Resistant Mycobacterium tuberculosis

Background: Tuberculosis (TB) is one of the most widespread and lethal infectious diseases worldwide. The emergence of drug-resistant TB has hampered effective TB treatment and control. Prokaryotic ubiquitin-like Protein-Proteasome System (PPS) contributes to the survival of Mycobacterium tuberculos...

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Veröffentlicht in:	Jundishapur journal of microbiology 2018-02, Vol.11 (2), p.1-7
Hauptverfasser:	Zhang, Shuai, Wen Zhang, Shun, Dong Wu, Jiang, Zhang, Jie, Tao Dong, Jiang, Yun Zhu, Hui, Wu, Fang, Jiang Zhang, Wan
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug resistance Electroporation Gene expression Infectious diseases Isoniazid Metabolism Minimum inhibitory concentration Mutation Mycobacterium tuberculosis Overexpression Plasmids Polymerase chain reaction Proteasomes Proteins Reverse transcription Statistics Studies Tuberculosis Ubiquitin
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