Strategies for radiolabelling antibody, antibody fragments and affibodies with fluorine-18 as tracers for positron emission tomography (PET)

[Display omitted] The use of fluorine-18 as a radionuclide for positron emission tomography (PET) has become increasingly popular over the last two decades and cancer and neurology clinical centres worldwide are increasingly establishing competence in this modality for diagnostic imaging. Progress h...

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Veröffentlicht in:	Journal of fluorine chemistry 2017-11, Vol.203, p.31-46
Hauptverfasser:	Clark, Joshua, O’Hagan, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibody Antibody fragment Bioconjugation Biomolecules Cancer Diagnostic systems Fluorine Fluorine-18 Fragmentation Fragments Half-life Labeling Low molecular weights Molecular weight Neurology Peptides Positron emission Positron emission tomography Proteins Radioisotopes Radiolabelling Tomography Tracers
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