A highly diastereoselective one-pot three-component 1,3-dipolar cycloaddition of cyclopropenes with azomethine ylides generated from 11H-indeno[1,2-b]-quinoxalin-11-ones

A simple and efficient method has been developed for the synthesis of complex compounds with spiro-fused 11H-indeno[1,2-b]quinoxaline and cyclopropa[a]pyrrolizine or azabicyclo[3.1.0]hexane moieties. All the products have been synthesized in good to high yields and excellent diastereoselectivity by...

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Veröffentlicht in:	Organic chemistry frontiers an international journal of organic chemistry 2018-02, Vol.5 (4), p.595-605
Hauptverfasser:	Filatov, A S, Knyazev, N A, Ryazantsev, M N, Suslonov, V V, Larina, A G, Molchanov, A P, Kostikov, R R, Boitsov, V M, Stepakov, A V
Format:	Artikel
Sprache:	eng
Schlagworte:	Amines Amino acids Anticancer properties Antitumor activity Complex compounds Cycloaddition Cytometry Derivatives Flow cytometry Leukemia Organic chemistry Organic compounds Peptides Quantum chemistry Quinoxaline
Online-Zugang:	Volltext
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