Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study

Summary Background Previous studies have suggested that trabectedin (ecteinascidin-743) could have antitumour activity in soft-tissue sarcoma. We aimed to study the usefulness of trabectedin in the treatment of patients with myxoid liposarcomas, a subtype of liposarcoma that is associated with speci...

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Veröffentlicht in:	The lancet oncology 2007-07, Vol.8 (7), p.595-602
Hauptverfasser:	Grosso, Federica, Dr, Jones, Robin L, MD, Demetri, George D, MD, Judson, Ian R, Prof, Blay, Jean-Yves, Prof, Le Cesne, Axel, MD, Sanfilippo, Roberta, MD, Casieri, Paola, PhD, Collini, Paola, MD, Dileo, Palma, MD, Spreafico, Carlo, MD, Stacchiotti, Silvia, MD, Tamborini, Elena, PhD, Tercero, Juan Carlos, PhD, Jimeno, Josè, MD, D'Incalci, Maurizio, MD, Gronchi, Alessandro, MD, Fletcher, Jonathan A, PhD, Pilotti, Silvana, MD, Casali, Paolo G, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic Agents, Alkylating - therapeutic use Chemotherapy Dioxoles - therapeutic use Disease-Free Survival Female Hematology, Oncology and Palliative Medicine Humans Liposarcoma Liposarcoma, Myxoid - drug therapy Liposarcoma, Myxoid - pathology Magnetic Resonance Imaging Male Medical prognosis Metastasis Middle Aged Oncogene Proteins, Fusion - genetics Oncogene Proteins, Fusion - metabolism Patients Response rates Retrospective Studies Sarcoma Tetrahydroisoquinolines - therapeutic use Tomography, X-Ray Computed
Online-Zugang:	Volltext
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