Association Between Matrix Metalloproteinase-3 Activity and Glomerular Filtration Rate and Albuminuria Status in Patients With Type 2 Diabetes Mellitus

Diabetic nephropathy is pictured as matrix accumulation and thickening of glomerular basal membrane. Matrix metalloproteinases (MMPs) are major proteases involved in extracellular matrix degradation. Moreover, plasminogen activator inhibitor-1 (PAI-1) primarily regulates plasmin dependent proteolysi...

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Veröffentlicht in:	Iranian journal of kidney diseases 2018-01, Vol.12 (1), p.40
Hauptverfasser:	Amanzadeh, Mina, Mota, Ali, Zarghami, Nosratollah, Abedi-Azar, Sima, Abroon, Sina, Akbarian, Naghmeh, Mihanfar, Aynaz, Rahmati-Yamchi, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Albuminuria - blood Albuminuria - diagnosis Albuminuria - etiology Albuminuria - physiopathology Area Under Curve Biomarkers - blood Case-Control Studies Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - diagnosis Diabetic Nephropathies - blood Diabetic Nephropathies - diagnosis Diabetic Nephropathies - etiology Diabetic Nephropathies - physiopathology Diabetic nephropathy Extracellular matrix Female Glomerular Filtration Rate Humans Kidney - physiopathology Male Matrix Metalloproteinase 3 - blood Middle Aged Plasminogen Activator Inhibitor 1 - blood Predictive Value of Tests Reproducibility of Results ROC Curve
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