Co-expression of anti-NF B RNA aptamers and siRNAs leads to maximal suppression of NF B activity in mammalian cells
The specific down-regulation of gene expression in cells is a powerful method for elucidating a gene's function. A common method for suppressing gene expression is the elimination of mRNA by RNAi or antisense. Alternatively, oligonucleotide-derived aptamers have been used as protein-directed ag...
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Veröffentlicht in: | Nucleic acids research 2006-03, Vol.34 (5), p.e36-e36 |
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Format: | Artikel |
Sprache: | eng |
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