HMGB1 interacts with human topoisomerase II  and stimulates its catalytic activity

DNA topoisomerase IIα (topo IIα) is an essential nuclear enzyme and its unique decatenation activity has been implicated in many aspects of chromosome dynamics such as chromosome replication and segregation during mitosis. Here we show that chromatin-associated protein HMGB1 (a member of the large f...

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Veröffentlicht in:	Nucleic acids research 2007-08, Vol.35 (15), p.5001-5013
Hauptverfasser:	Stros, M., Bacikova, A., Polanska, E., Stokrova, J., Strauss, F.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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