Roles for insulin-like growth factor I and transforming growth factor-(beta) in fibrotic lung disease

Idiopathic pulmonary fibrosis (IPF) is a lung disease that is characterized by epithelial cell damage and areas of denuded basement membrane resulting in inflammation, fibroblast proliferation, excessive extracellular matrix (ECM) deposition, and remodeling of alveolar gas exchange units. The progre...

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Veröffentlicht in:	Chest 2002-12, Vol.122 (6), p.S289
Hauptverfasser:	Krein, Peter M, Winston, Brent W
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell division Connective tissue Cytokines Extracellular matrix Fibroblasts Inflammation Insulin Insulin-like growth factors Lung diseases Lungs Pulmonary fibrosis Roles Tumor necrosis factor-TNF
Online-Zugang:	Volltext
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