Modulation of the molecular composition of large conductance, Ca^sup 2+^ activated K^sup +^ channels in vascular smooth muscle during hypertension

Hypertension is a clinical syndrome characterized by increased vascular tone. However, the molecular mechanisms underlying vascular dysfunction during acquired hypertension remain unresolved. Localized intracellular Ca2+ release events through ryanodine receptors (Ca2+ sparks) in the sarcoplasmic re...

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Veröffentlicht in:	The Journal of clinical investigation 2003-09, Vol.112 (5), p.717
Hauptverfasser:	Amberg, Gregory C, Bonev, Adrian D, Rossow, Charles F, Nelson, Mark T, Santana, Luis F
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical research Blood pressure Cardiovascular disease Communication Hypertension Hypotheses Muscle function Protons Smooth muscle Software
Online-Zugang:	Volltext
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