A peripheral circulating compartment of natural naive CD4^sup +^ Tregs
CD4CD25 Tregs play a central role in the maintenance of peripheral self tolerance by keeping autoreactive T cells in check. Whereas the thymic origin of CD4CD25 Tregs, as a distinct lineage, has been inferred, understanding of their developmental pathways has remained elusive. In both mice and human...
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| Veröffentlicht in: | The Journal of clinical investigation 2005-07, Vol.115 (7), p.1953 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
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