Pleurodesis Is Inhibited by Anti-Vascular Endothelial Growth Factor Antibody

The intrapleural injection of transforming growth factor (TGF)-β2 produces pleurodesis in rabbits associated with large pleural effusions. This study investigated whether anti-vascular endothelial growth factor (VEGF) antibody has any effect on the fluid production or the pleurodesis induced by TGF-...

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Veröffentlicht in:	Chest 2005-09, Vol.128 (3), p.1790-1797
Hauptverfasser:	Guo, Yubiao B., Kalomenidis, Ioannis, Hawthorne, Michael, Parman, Kelly S., Lane, Kirk B., Light, Richard W.
Format:	Artikel
Sprache:	eng
Schlagworte:	angiogenesis Animals Antibodies - administration & dosage Cytokines - administration & dosage Cytokines - adverse effects Infusions, Parenteral Neovascularization, Pathologic - prevention & control pleura Pleura - blood supply Pleura - drug effects Pleural Effusion - chemically induced Pleural Effusion - prevention & control pleurodesis Pleurodesis - methods Rabbits Transforming Growth Factor beta - administration & dosage Transforming Growth Factor beta - adverse effects Transforming Growth Factor beta2 transforming growth factor-β2 vascular endothelial growth factor Vascular Endothelial Growth Factor A - administration & dosage
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