Pulmonary Toxicity in Patients With Advanced-Stage Germ Cell Tumors Receiving Bleomycin With and Without Granulocyte Colony Stimulating Factor

The purpose of this study is to determine whether co-administration of granulocyte colony stimulating factor (G-CSF) and bleomycin results in enhanced pulmonary toxicity compared with bleomycin alone. A retrospective analysis comparing two groups of patients with advanced germ cell tumors receiving...

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Veröffentlicht in:	Chest 1997-03, Vol.111 (3), p.657-660
Hauptverfasser:	Saxman, Scott B., Nichols, Craig R., Einhorn, Lawrence H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antimetabolites, Antineoplastic - administration & dosage Antimetabolites, Antineoplastic - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Bleomycin Bleomycin - administration & dosage Bleomycin - adverse effects Cancer Chemotherapy Cisplatin - administration & dosage Cisplatin - adverse effects Complications and side effects Confidence intervals Drug toxicity and drugs side effects treatment Etoposide - administration & dosage Etoposide - adverse effects Germ cell tumors Germinoma - drug therapy Granulocyte colony-stimulating factor Granulocyte Colony-Stimulating Factor - administration & dosage Granulocyte Colony-Stimulating Factor - adverse effects Granulocytes Growth factors Humans Lung - drug effects Lungs Male Medical sciences Middle Aged Pharmacology. Drug treatments Physiological aspects pulmonary toxicity Radiation therapy Retrospective Studies Testicular cancer Toxicity Toxicity: respiratory system, ent, stomatology Tumors
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